Dr. Andrew Adamatzky from University of the West of England Bristol just published a paper in arXiv that outlines a general way of constructing a biological computer that can take advantage of this organism's behavior.
Plasmodium Computing
If you've ever wondered about the origin of intelligence, take a few moments to study a being called Physarum polycephalum. This single-celled organism can find the shortest way through mazes, it can anticipate periodic events and now its learning how to carry out simple computations.
International Center of Unconventional Computing
Plasmodium of Physarum polycephalum: illustrations to papers
Plasmodium on the micro-electrode array
Wave-fragment propagation similar to that in sub-excitable BZ systems.
Plasmodium on aluminum foil
Steiner tree computer by plasmodium
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